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Saving,Girls,Cancer
Wednesday, June 1, 2011
Saving A Girl's Leg From Bone Cancer
(Ivanhoe Newswire) -- 2,300 cases of bone cancer are diagnosed each year in the United States. (Source: Medical Headlines From Ivanhoe.com)
All-in-one live: genes trapped, tagged and conditionally broken
Nature Methods 8, 466 (2011). doi:10.1038/nmeth.1617Author: Mary C MullinsA transposon-insertion method can trap and mutate genes while simultaneously revealing their spatiotemporal expression pattern, all in a conditional manner in the live, transparent zebrafish. (Source: Nature Methods)
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Allinone,genes,trapped,tagged,conditionally,broken
Hepatotoxicity from abuse of kratom: first reported case
3.5 out of 5 starsIntrahepatic Cholestasis Following Abuse of Powdered Kratom (Mitragyna speciosa) Kapp FG et al. J Med Toxicol 2011 April 29. [Epub ahead of print]AbstractKratom is a psychoactive leaf from the southeast asian tree Mitragyna speciosa (picture). This tree is related to the plants that produce coffee. Because there are a number of different alkaloids in kratom and because some of its actions are dose related, ingesting the leaf has been associated with a variety of effects, including sedation, analgesia, increased energy, a sense of well being, and improved mood. Of the major alkaloids, mitragynine is a stimulant and 7-hydroxymitragyine a sedative and analgesic, acting primarily as an agonist at the µ-opioid receptor.This case report, from Germany, describes a 25-y...
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Hepatotoxicity,abuse,kratom,first,reported
The Effects Of Celiac Disease On Bone Mineral Density Are More Pronounced In Lumbar Spine Than Femoral Neck
Patients with celiac disease are more than 4.5 times more likely to develop osteoporosis compared to healthy people in an age and gender matched cohort with no identifiable risk factors for osteoporosis, according to a study presented at the EULAR 2011 Annual Congress. The British study of 1,030 people compares the extent of bone mineral density (BMD)* loss - a common measure of osteoporosis - in two physical locations in the body... (Source: Health News from Medical News Today)
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Effects,Celiac,Disease,Mineral,Density,Pronounced,Lumbar,Spine,Femoral
Thursday, May 26, 2011
USPSTF needs overhaul, groups say
The Agency for Healthcare Research and Quality desperately needs to restructure the U.S. Preventive Services Task Force (USPSTF), which more than a dozen organizations claim suffers from a lack of transparency and nonrepresentation of key medical specialties. (Source: Health Imaging News)
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USPSTF,needs,overhaul,groups
Results of national audit of falls and bone health in older people
This report contains the findings from the National Audit of Falls and Bone Health in Older People, which examined the organisation and commissioning of services (both in acute and primary care) provided to older people for falls prevention and bone health, and the clinical care provided for those that have fallen and suffered a fracture. This audit was commissioned by the Healthcare Quality Improvement Partnership (HQIP) as part of the National Clinical Audit and Patient Outcomes Programme (NCAPOP). Although some improvements have been made since previous audits, major variations between organisations persist and deficiencies in care remain widespread. The document summarises key recommendations made in relation to the following Department of Health objectives: ...
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Results,national,audit,falls,health,older,people
What are the factors of residual pain after uncomplicated TKA?
Conclusion The identification of these high-risk patients is critical so that a surgeon can provide detailed preoperative education in order to give these patients a realistic expectation of their possible satisfaction following TKA. Level of evidence V. Content Type Journal ArticlePages 1-7DOI 10.1007/s00167-011-1549-2AuthorsMichel P. Bonnin, Centre Orthopédique Santy, 24 Av Paul Santy, 69008 Lyon, FranceLuca Basiglini, Centre Orthopédique Santy, 24 Av Paul Santy, 69008 Lyon, FranceH. A. Pooler Archbold, Centre Orthopédique Santy, 24 Av Paul Santy, 69008 Lyon, FranceJournal Knee Surgery, Sports Traumatology, ArthroscopyOnline ISSN 1433-7347Print ISSN 0942-2056 (Source: Knee Surgery, Sports Traumatology, Arthroscopy)
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factors,residual,after,uncomplicated
Positive contrast magnetic resonance bursography for assessment of the navicular bursa and surrounding soft tissues
Magnetic resonance (MR) imaging is often performed to determine the cause of palmar heel pain. We evaluated how distension of the navicular bursa affected the MR appearance of the navicular bursa and associated structures. An MR evaluation was performed on normal cadaver limbs and cadaver limbs from horses with lameness localized to the foot. The normal navicular bursae were injected with 2, 4, or 6 ml of solution. The bursae of the feet from lame horses were injected with 4 or 6 ml, and the MR study was repeated. All bursae were examined grossly to verify the presence or absence of adhesions. Clinical patients that had initial MRI abnormalities suggesting adhesions were also evaluated. Distension of the proximal recess of the normal navicular bursa, proximal to the collateral sesamoid...
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Positive,contrast,magnetic,resonance,bursography,assessment,navicular,bursa,surrounding,tissues
Retrospective investigation of prognostic indicators for adult horses with infection of a synovial structure
Conclusions Of the variables available at presentation, only evidence of bone or tendon involvement negatively affected survival and athletic function. During treatment of synovial sepsis, analysis of synovial fluid at 4–6 days and bacterial culture results have prognostic value. (Source: Australian Veterinary Journal)
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Retrospective,investigation,prognostic,indicators,adult,horses,infection,synovial,structure
Salvage of foot with extensive giant cell tumour with transfer of vascularised fibular bone graft
We report a case with extensive involvement of all the tarsal bones and metatarsal bases in a young adult. After excision his foot was reconstructed with vascularised bone flap. We were able to save his foot after a wide local excision and reconstruction with free fibula graft. Graft united early and showed excellent remodelling because of good vascularity. We feel that this method deserves consideration as a last attempt to salvage functional foot in disease like this. (Source: Indian Journal of Plastic Surgery)
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Salvage,extensive,giant,tumour,transfer,vascularised,fibular,graft
Prognostic claim for VerifyNow platelet test in EU
UPDATED // The platelet-function test VerifyNow P2Y12 has been granted a CE mark in Europe for a new, updated claim for prognostic use to help identify patients with high residual platelet...For complete story visit theheart.org. (Source: theHeart.org)
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Prognostic,claim,VerifyNow,platelet
Use of a Decision Aid to Improve Treatment Decisions in Osteoporosis: The Osteoporosis Choice Randomized Trial
Conclusion: A decision aid improved the quality of clinical decisions about bisphosphonate therapy in at-risk postmenopausal women, did not affect start rates, and may have improved adherence. (Source: The American Journal of Medicine)
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Decision,Improve,Treatment,Decisions,Osteoporosis,Osteoporosis,Choice,Randomized,Trial
Wednesday, May 25, 2011
Your Bone Health
Source: HealthDay - Related MedlinePlus Pages: Healthy Living, Osteoporosis (Source: MedlinePlus Health News)
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Health
What constitutes “normal” 25(OH)D?
Over the past decade, we have learned that calciferol has a number of very important biologic functions beyond its skeletal effects. This was nicely reviewed in a recent Medical Progress report by Russell Chesney (J Pediatr 2011;156:698-703). This understanding has resulted in a number of studies examining the frequency of calciferol deficiency in various groups. A problem of these studies, however, has been defining “sufficiency” of this analyte. Studies that have used measures of bone turnover or parathyroid hormone as evidence of sufficiency may not reflect the levels that are “normal” for calciferol's non-skeletal effects. (Source: The Journal of Pediatrics)
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constitutes,normal,25OHD
VIDEO: Football unites transplant pair
A Merseyside man who gave bone marrow meets the leukaemia patient whose life was saved by his donation. (Source: BBC News | Health | UK Edition)
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VIDEO,Football,unites,transplant
Vitamin D2 or vitamin D3 supplementation in daily dose: Are they equivalent?
The objectives of this study were 1: to compare the efficacy of daily doses of 800UI D2 and D3 in healthy women >65years. 2: to evaluate the effectiveness of the administration of vitamin D, both in drops and tablets. Population and methods: 27 ambulatory women, mean age (X±SD) 77.1±6.8years in winter. Serum calcium, phosphorus, 25OHD, bone alkaline phosphatase and urine calcium/creatinine were evaluated at baseline and 7, 28 and 45days after supplementation with two daily regimens: G1: 800IU D3 (tablets) G2: 800IU D2 (drops). Statistics: SPSS 11.0 Chicago. IL, USA. Results: at baseline 25OHD levels (ng/ml) were similar in both groups (G1: 14.0±4.8 G2: 12.6±4.5; ns). 91.7% of the population showed deficient 25OHD levels ( (Source: Bone)
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Vitamin,vitamin,supplementation,daily,equivalent
Short implants in posterior jaws. A prospective 1-year study.
Conclusions: One year after loading, 7 mm short implants provided good success rates (95% at patient level and implant level) suggesting that the use of short implants is a viable concept, however longer follow-ups are needed to confirm these preliminary results. PMID: 21594219 [PubMed - in process] (Source: European Journal of Oral Implantology)
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Short,implants,posterior,prospective,1year,study
Spontaneous bilateral distal ulna fracture: an unusual complication in a rheumatoid patient
We report a case of bilateral stress fractures of the ulna in an elderly patient with rheumatoid arthritis, and literature on this condition is reviewed. Prompt recognition and activity modification are essential to treat this rare injury. Recovery can take up to 12 weeks. Content Type Journal ArticlePages 1-4DOI 10.1007/s10195-011-0140-4AuthorsSantosh Venkatachalam, Department of Orthopaedics, Sunderland Royal Hospital, Kayll Road, Sunderland, SR4 7TP UKPaul Dixon, Department of Orthopaedics, Sunderland Royal Hospital, Kayll Road, Sunderland, SR4 7TP UKJournal Journal of Orthopaedics and TraumatologyOnline ISSN 1590-9999Print ISSN 1590-9921 (Source: Journal of Orthopaedics and Traumatology)
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Spontaneous,bilateral,distal,fracture,unusual,complication,rheumatoid,patient
Really?: The Claim: Playing a Wind Instrument Causes Respiratory Infection
While researchers have not looked specifically at infection rates in musicians, there have been numerous case reports of lung problems linked to instruments. (Source: NYT Health)
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Really,Claim,Playing,Instrument,Causes,Respiratory,Infection
The Interface Between Medical Oncology and Supportive and Palliative Cancer Care
This article examines the interface between medical oncology and supportive and palliative care to emphasize how each can benefit from the others. (Source: Seminars in Oncology)
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Interface,Between,Medical,Oncology,Supportive,Palliative,Cancer
Ruling a victory for Ohio tort reform measures, physicians say
The state's high court decides that a patient's emotional distress claim must be included in a medical liability lawsuit and cannot stand alone. (Source: American Medical News - PROFESSION)
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Ruling,victory,reform,measures,physicians
Vitamin D2 and D3 supplementation in healthy adolescents from Ushuaia, Argentina
In order to improve vitamin D status of healthy adolescents from Ushuaia (55° S), three supplementations of 100,000IU of vitamin D2 (ergocalciferol) or vitamin D3 (cholecalciferol) were administered every three months: during fall (March), winter (June) and spring (September). Serum 25-hydroxyvitamin D (25OHD) was measured before the study, a month after the first supplementation, and two months after receiving the third supplementation (September 2008, April 2009 and November 2009). We studied 34 healthy adolescents, age (mean±SD) 18.5±2years old, 23 girls and 11 boys. None had received previous vitamin D. Seventeen adolescents received vitamin D2 and 17 received vitamin D3. Basal levels of serum 25OHD were 13.4±6.3ng/ml (range 4–26) in September/spring 2008 (D2 group: 14.6±6.4, D3...
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Vitamin,supplementation,healthy,adolescents,Ushuaia,Argentina
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