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Hepatotoxicity,abuse,kratom,first,reported
Wednesday, June 1, 2011
Hepatotoxicity from abuse of kratom: first reported case
3.5 out of 5 starsIntrahepatic Cholestasis Following Abuse of Powdered Kratom (Mitragyna speciosa) Kapp FG et al. J Med Toxicol 2011 April 29. [Epub ahead of print]AbstractKratom is a psychoactive leaf from the southeast asian tree Mitragyna speciosa (picture). This tree is related to the plants that produce coffee. Because there are a number of different alkaloids in kratom and because some of its actions are dose related, ingesting the leaf has been associated with a variety of effects, including sedation, analgesia, increased energy, a sense of well being, and improved mood. Of the major alkaloids, mitragynine is a stimulant and 7-hydroxymitragyine a sedative and analgesic, acting primarily as an agonist at the ยต-opioid receptor.This case report, from Germany, describes a 25-y...
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